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1234 0/01 0/1 0/0 520 0/01 0/10 0/1 320 0/10 0/01 0/0 414 0/1 01/01 0/10 86 0/10 0/1 0 1/1 434 01/1 01/1 0/0 241 01/1 10/1 0/0 1 10/1 0/1 0 0 0/0 |
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Overall this data is consistent with column 1 (NA12878) being the child. Lines marked with an * are inconsistant: 34 0/1 0/1 0/0 20 0/1 0/0 0/1 20 0/0 0/1 0/0 14 0/1 1/1 0/0 # middle can't be child 6 0/0 0/1 0/1 4 1/1 1/1 0/0 * No mendelian combination exists 1 1/1 0/1 0/0 1 0/1 0/0 0/0 | ||
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Here is my interpretation of the data: 1) This method effectively looks at a very narrow genomic region, probably within a homologous recombination block. 2) The most telling data: the child will have heterozygous SNPs from two homozygous parents. 3) So all this data is consistent with column 1 (NA12878) being the child: 12 0/0 0/1 0/0 "Outlier" data are: 3 0/1 0/0 0/0 1 1/1 0/1 0/0* This is, in fact, the correct assessment - NA12878 is the child. |
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