General introduction

Overall Course Learning Objectives

• Be capable of navigating a Linux operating system and TACC's Lonestar system in particular
• Understand common workflows and tools for NGS analysis:
  • "Re-sequencing" - comparing raw sequence data to a reference genome, calling variants, and annotating variants DNA sequencing data
  • RNA-seq - quantifying gene expression and determining splice variation from RNA-seq data
  • de novo genome assembly and annotation

Learning Objectives: Day 1, Part 1: Linux/TACC Introduction

• Understand the broadest definition of "biomedical/biological informatics" and where this course fits in
• Learn and practice essential Linux concepts and commands, including where to get more help & information
• Learn and practice working with TACC systems (Lonestar in particular)