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Annovar is installed on fourierseq at /opt/annovar. Annovar is a useful tool for functional annotation of SNPs. It will annotate whether the snp is known/novel, whether it is an exonic region or otherwise, the amino acid changes it would cause and scores to determine the damage potential of the snp.

To generate a summary annovar report on your SNPs, using Human hg19 genome, follow the steps below:

1. Convert vcf snp file to annovar format

convert2annovar.pl -format vcf4 --inlcudeinfo out.vcf > out.vcf.annovar

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